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Is Aspirin Polar?

Aspirin or acetylsalicylic acid (ASA) is non-polar, although it does have one alcohol group. The molecule is regarded non-polar owing to the large section of non-polarity. It will have a slight dipole but not enough to cause hydrogen bonds. It is slightly soluble in water that is less than 0.1 g per/100 ml at 23 degree C. Since it is non-polar, it is otherwise insoluble in water. Also, when aspirin hits acid pH in the stomach, it can lose hydrogen that can change the polarity to become more soluble. Remember, if aspirin is taken after consuming alcohol, it may prove fatal as they produce some of the most potent toxic compounds.

by Susan White on Tue, 11/16/2010 - 21:55

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